NAPA Protein (His tag)
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- Target See all NAPA Proteins
- NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NAPA protein is labelled with His tag.
- Purpose
- Recombinant Human SNAP-alpha/NAPA Protein (His Tag)
- Sequence
- Met 1-Arg295
- Characteristics
- Recombinant Human alpha-Soluble NSF Attachment Protein is produced by our E.coli expression system and the target gene encoding Met1-Arg295 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product NAPA Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))
- Alternative Name
- SNAP-alpha/NAPA (NAPA Products)
- Synonyms
- SNAPA Protein, wu:fa26c04 Protein, zgc:63906 Protein, napb Protein, 1500039N14Rik Protein, AW209189 Protein, RA81 Protein, SNARE Protein, a-SNAP Protein, hyh Protein, alpha-SNAP Protein, Alpha-SNAP Protein, NSF attachment protein alpha Protein, N-ethylmaleimide-sensitive factor attachment protein, alpha b Protein, NSF attachment protein alpha L homeolog Protein, N-ethylmaleimide-sensitive factor attachment protein, alpha Protein, N-ethylmaleimide sensitive fusion protein attachment protein alpha Protein, soluble NSF attachment protein Protein, NAPA Protein, napab Protein, napa.L Protein, napa Protein, EHI_000300 Protein, Napa Protein, LOC102577508 Protein
- Background
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Background: α-Soluble NSF Attachment Protein (SNAP-α) is a member of the SNAP (Soluble NSF Attachment Protein) family. SNAP-α interacts with PRKCABP and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. SNAP-α is required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. SNAP-α is in charge of the binding of NSF and therefore the formation of a 20S fusion particle.
Synonym: Alpha-Soluble NSF Attachment Protein, SNAP-Alpha, N-Ethylmaleimide-Sensitive Factor Attachment Protein Alpha, NAPA, SNAPA
- Molecular Weight
- 35.4 kDa
- UniProt
- P54920
- Pathways
- Synaptic Vesicle Exocytosis, Asymmetric Protein Localization
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