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OBFC1 Protein (His tag)

OBFC1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318845
  • Target See all OBFC1 Proteins
    OBFC1 (Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This OBFC1 protein is labelled with His tag.
    Purpose
    Recombinant Human OBFC1/STN1 Protein (His Tag)
    Sequence
    Met 1-Phe368
    Characteristics
    Recombinant Human Oligosaccharide-Binding Fold-Containing Protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Phe368 is expressed with a 6His tag at the N-terminus.
    Purity
    > 85 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product OBFC1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 1 mM DTT, pH 8.0.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    OBFC1 (Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1))
    Alternative Name
    OBFC1/STN1 (OBFC1 Products)
    Synonyms
    AAF-44 Protein, AAF44 Protein, RP11-541N10.2 Protein, RPA-32 Protein, STN1 Protein, bA541N10.2 Protein, 0610009H20Rik Protein, 2310057J23Rik Protein, AI413458 Protein, zgc:64174 Protein, ATSTN1 Protein, F10K1.17 Protein, F10K1_17 Protein, STN1, CST complex subunit Protein, Nucleic acid-binding, OB-fold-like protein Protein, STN1 Protein, Stn1 Protein, stn1 Protein
    Background

    Background: CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.

    Synonym: CST Complex Subunit STN1, Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1, Suppressor of Cdc Thirteen Homolog, OBFC1, STN1

    Molecular Weight
    44.2 kDa
    UniProt
    Q9H668
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