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PDAP1 Protein (His tag)

PDAP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318877
  • Target See all PDAP1 Proteins
    PDAP1 (PDGFA Associated Protein 1 (PDAP1))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    Human
    Source
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PDAP1 protein is labelled with His tag.
    Purpose
    Recombinant Human PDAP1/PAP Protein (His Tag)
    Sequence
    Met 1-Lys181
    Characteristics
    Recombinant Human PDGF-Associated Protein is produced by our E.coli expression system and the target gene encoding Met1-Lys181 is expressed with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product PDAP1 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Tris, 100 mM NaCl, 0.1 mM PMSF, 2 mM DTT, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    PDAP1 (PDGFA Associated Protein 1 (PDAP1))
    Alternative Name
    PDAP1/PAP (PDAP1 Products)
    Synonyms
    pdap1 Protein, zgc:56213 Protein, HASPP28 Protein, PAP Protein, PAP1 Protein, Haspp28 Protein, pdgfa associated protein 1b Protein, 28 kDa heat- and acid-stable phosphoprotein Protein, PDGFA associated protein 1 Protein, pdap1b Protein, CpipJ_CPIJ013582 Protein, PDAP1 Protein, Pdap1 Protein
    Background

    Background: Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. PDGF-Associated Protein (PAP) is a phosphoprotein that may enhance PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. PDAP1 expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha.

    Synonym: 28 kDa Heat- and Acid-Stable Phosphoprotein, PDGF-Associated Protein, PAP, PDGFA-Associated Protein 1, PAP1, PDAP1, HASPP28

    Molecular Weight
    22.8 kDa
    UniProt
    Q13442
    Pathways
    Platelet-derived growth Factor Receptor Signaling
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