PI3 Protein (His tag)
-
- Target See all PI3 Proteins
- PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Human Cells
- Purification tag / Conjugate
- This PI3 protein is labelled with His tag.
- Purpose
- Recombinant Human PI3/Elafin Protein (His Tag)
- Sequence
- Ala23-Gln117
- Characteristics
- Recombinant Human Elafin is produced by our Mammalian expression system and the target gene encoding Ala23-Gln117 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PI3 Protein
-
Peptidase Inhibitor 3, Skin-Derived (PI3) (AA 1-117) protein (GST tag)
PI3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Peptidase Inhibitor 3, Skin-Derived (PI3) (AA 61-117) protein (His-DYKDDDDK-Strep II Tag)PI3 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Peptidase Inhibitor 3, Skin-Derived (PI3) (AA 61-117) protein (His tag)Crystallography grade PI3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Peptidase Inhibitor 3, Skin-Derived (PI3) (AA 61-117) protein (His-SUMO Tag)PI3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Peptidase Inhibitor 3, Skin-Derived (PI3) (AA 23-117) protein (His tag)PI3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % by SDS - PAGE SDS
Peptidase Inhibitor 3, Skin-Derived (PI3) (AA 61-117) protein (His tag)PI3 Origin: Human Host: Yeast Recombinant > 90 % SDS
Peptidase Inhibitor 3, Skin-Derived (PI3) protein (Myc-DYKDDDDK Tag)PI3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Target
- PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
- Alternative Name
- PI3/Elafin (PI3 Products)
- Synonyms
- ESI Protein, SKALP Protein, WAP3 Protein, WFDC14 Protein, cementoin Protein, trappin-2 Protein, TRAPPIN-2 Protein, elafin Protein, peptidase inhibitor 3 Protein, peptidase inhibitor 3, skin-derived (SKALP) Protein, PI3 Protein
- Background
-
Background: Elafin is a secreted protein. Elafin consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain serves as an anchor to localize Elafin covalently to specific sites on extracellular matrix proteins. It is shown that Elafin can be used as a biomarker for graft versus host disease of the skin. Elafin is expressed in the skin during wound healing through activation of the epidermal growth factor receptor. Elafin may prevent elastase-mediated tissue proteolysis.
Synonym: Elafin, Elastase-Specific Inhibitor, ESI, Peptidase Inhibitor 3, PI-3, Protease inhibitor WAP3, Skin-Derived Antileukoproteinase, SKALP, WAP Four-Disulfide Core Domain Protein 14, PI3, WAP3, WFDC14
- Molecular Weight
- 11.0 kDa
- UniProt
- P19957
-
