PIN4 Protein (His tag)
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- Target See all PIN4 Proteins
- PIN4 (Peptidyl Prolyl Cis/Trans Isomerase NIMA Interacting 4 Protein (PIN4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PIN4 protein is labelled with His tag.
- Purpose
- Recombinant Human Parvulin-14/PIN4 Protein (His Tag)
- Sequence
- Met 1-Lys156
- Characteristics
- Recombinant Human Parvulin-14 is produced by our E.coli expression system and the target gene encoding Met1-Lys156 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PIN4 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- PIN4 (Peptidyl Prolyl Cis/Trans Isomerase NIMA Interacting 4 Protein (PIN4))
- Alternative Name
- Parvulin-14/PIN4 (PIN4 Products)
- Synonyms
- 2410002I22Rik Protein, EPVH Protein, Par14 Protein, PAR14 Protein, PAR17 Protein, zgc:110008 Protein, peptidylprolyl cis/trans isomerase, NIMA-interacting 4 Protein, protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) Protein, protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) Protein, PIN4 Protein, Pin4 Protein, pin4 Protein
- Background
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Background: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, PIN4 protein binds to double-stranded DNA under physiological salt conditions. PIN4 is involved as a ribosomal RNA processing factor in ribosome biogenesis. The PAR14 binds to tightly bent AT-rich stretches of double-stranded DNA, but PAR17 binds to double-stranded DNA.
Synonym: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, Parvulin-14, Parvulin-17, Peptidyl-prolyl cis-trans isomerase Pin4, Peptidyl-prolyl cis/trans isomerase EPVH, Rotamase Pin4, PIN4,
- Molecular Weight
- 18.8 kDa
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