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PPIC Protein (TRX tag,His tag)

PPIC Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318367
  • Target See all PPIC Proteins
    PPIC (Peptidylprolyl Isomerase C (Cyclophilin C) (PPIC))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PPIC protein is labelled with TRX tag,His tag.
    Purpose
    Recombinant Human Cyclophilin C/PPIC Protein (His&Trx Tag)
    Sequence
    Lys31-Asp182
    Characteristics
    Recombinant Human Peptidyl-Prolyl cis-trans Isomerase C is produced by our E.coli expression system and the target gene encoding Lys31-Asp182 is expressed with a Trx, 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PPIC Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 10 % Glycerol, pH 7.4.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    PPIC (Peptidylprolyl Isomerase C (Cyclophilin C) (PPIC))
    Alternative Name
    Cyclophilin C/PPIC (PPIC Products)
    Synonyms
    cypc Protein, CyP-20c Protein, CYPC Protein, peptidylprolyl isomerase C Protein, peptidylprolyl isomerase C (cyclophilin C) L homeolog Protein, PPIC Protein, ppic.L Protein, Ppic Protein
    Background

    Background: Cyclophilin C is an enzyme (EC 5.2.1.8) found in both prokaryotes and eukaryotes that interconverts the cis and trans isomers of peptide bonds with the amino acid proline. Proline has an unusually conformationally restrained peptide bond due to its cyclic structure with its side chain bonded to its secondary amine nitrogen. Most amino acids have a strong energetic preference for the trans peptide bond conformation due to steric hindrance, but prolines unusual structure stabilizes the cis form so that both isomers are populated under biologically relevant conditions. Proteins with prolyl isomerase activity include cyclophilin, FKBPs, and parvulin, although larger proteins can also contain prolyl isomerase domains.

    Synonym: Peptidyl-Prolyl Cis-Trans Isomerase C, PPIase C, Cyclophilin C, Rotamase C, PPIC, CYPC

    Molecular Weight
    33.8 kDa
    UniProt
    P45877
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