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PSG6 Protein (His tag)

PSG6 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 87 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317194
  • Target See all PSG6 Proteins
    PSG6 (Pregnancy Specific beta-1-Glycoprotein 6 (PSG6))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This PSG6 protein is labelled with His tag.
    Purpose
    Recombinant Human PSG6/PSG10 Protein (His Tag)
    Sequence
    Met 1-His 424
    Characteristics
    A DNA sequence encoding the human PSG6 (Met 1-His 424) (NP_001027020) was expressed, with a C-terminal polyhistidine tag.
    Purity
    > 87 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PSG6 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    PSG6 (Pregnancy Specific beta-1-Glycoprotein 6 (PSG6))
    Alternative Name
    PSG6/PSG10 (PSG6 Products)
    Synonyms
    PSBG-10 Protein, PSBG-12 Protein, PSBG-6 Protein, PSG10 Protein, PSGGB Protein, PSG6 Protein, PSG3 Protein, pregnancy specific beta-1-glycoprotein 6 Protein, pregnancy-specific beta-1-glycoprotein 4 Protein, PSG6 Protein, LOC456082 Protein
    Background

    Background: PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins which are produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most profound suppression of MS disease attacks. PSGs regulate T-cell function. The regulation of T-cell function during pregnancy is likely the result of significant hormonal changes and may well involve immunoregulatory proteins derived from the placenta. Pregnancy specific glycoproteins (PSGs) are the most abundant placentally derived glycoproteins in the maternal serum. PSG1, PSG6, PSG6N, and PSG11 induce dose-dependent secretion of anti-inflammatory cytokines by human monocytes. Human and murine PSGs exhibit cross-species activity.

    Synonym: CGM3,PSBG-10,PSBG-12,PSBG-6,PSG10,PSG12,PSG6,PSGGB

    Molecular Weight
    45.2 kDa
    NCBI Accession
    NP_001027020
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