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Enkephalin Protein (His tag)

PENK Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318934
  • Target See all Enkephalin (PENK) Proteins
    Enkephalin (PENK) (Proenkephalin (PENK))
    Protein Type
    Recombinant
    Origin
    • 6
    • 3
    • 2
    • 1
    • 1
    Human
    Source
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This Enkephalin protein is labelled with His tag.
    Purpose
    Recombinant Human Proenkephalin-A/PENK Protein (His Tag)
    Sequence
    Glu25-Phe267
    Characteristics
    Recombinant Human Proenkephalin-A is produced by our Mammalian expression system and the target gene encoding Glu25-Phe267 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product PENK Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Enkephalin (PENK) (Proenkephalin (PENK))
    Alternative Name
    Proenkephalin-A/PENK (PENK Products)
    Synonyms
    AI326464 Protein, ENK Protein, PPA Protein, Penk1 Protein, PENK Protein, penk Protein, Enk Protein, Penk-rs Protein, Penk2 Protein, penkl Protein, zgc:73353 Protein, Penk Protein, proenkephalin Protein, preproenkephalin Protein, proenkephalin b Protein, proenkephalin L homeolog Protein, proenkephalin a Protein, PENK Protein, Penk Protein, penk Protein, penkb Protein, penk.L Protein, penka Protein
    Background

    Background: Proenkephalin-A is a secreted protein that belongs to the opioid neuropeptide precursor family. Proenkephalin-A is an endogenous opioid polypeptide hormone which, via proteolyic cleavage, produces the enkephalin peptides [Met]enkephalin, and to a lesser extent, [Leu]enkephalin. Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. Proenkephalin-A (114-133) and Proenkephalin-A (237-258) increase glutamate release in the striatum. Proenkephalin-A (114-133) decreases GABA concentration in the striatum.

    Synonym: Proenkephalin-A, Synenkephalin, Met-Enkephalin, Leu-Enkephalin, PENK

    Molecular Weight
    29.2 kDa
    UniProt
    P01210
    Pathways
    Stem Cell Maintenance
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