PA2G4 Protein (His tag)

Catalog No. ABIN7317325

Product Details

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PA2G4 protein is labelled with His tag.

Purpose: Recombinant Human EBP1/PA2G4 Protein (His Tag)

Sequence: Ser 2-Asp 394

Characteristics: A DNA sequence encoding the human PA2G4 (Q9UQ80) (Ser 2-Asp 394) was expressed, with a polyhistide tag at the N-terminus.

Purity: > 92 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 0.5M NaCl, pH 8.0

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Alternative Name: EBP1/PA2G4 (PA2G4 Products)

Synonyms: EBP1 Protein, HG4-1 Protein, p38-2G4 Protein, Ebp1 Protein, pa2g4 Protein, si:dz150i12.2 Protein, wu:fb19b11 Protein, wu:ft56d05 Protein, zgc:86732 Protein, ebp1 Protein, hg4-1 Protein, p38-2g4 Protein, pa2g4-a Protein, PA2G4 Protein, DKFZp469G2132 Protein, Pa2g4 Protein, MGC81621 Protein, 38kDa Protein, AA672939 Protein, Plfap Protein, proliferation-associated 2G4 Protein, proliferation-associated 2G4, a Protein, proliferation-associated 2G4, 38kDa Protein, proliferation-associated 2G4 L homeolog Protein, proliferation-associated protein 2G4 Protein, proliferation-associated 2G4 S homeolog Protein, proliferation-associated protein 2G4 pseudogene Protein, PA2G4 Protein, Pa2g4 Protein, pa2g4a Protein, pa2g4.L Protein, pa2g4 Protein, LOC100519773 Protein, pa2g4.S Protein, LOC693641 Protein

Background:

Background: EBP1, also known as PA2G4, is an RNA-binding protein which belongs to the peptidase M24 family. It can be detected n several cell lines tested, including primary and transformed cell lines. EBP1 also present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein is a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. PA2G4 can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. EBP1 has been implicated in growth inhibition and the induction of differentiation of human cancer cells. It seems to be involved in growth regulation. EBP1 also mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site).

Synonym: EBP1,HG4-1,p38-2G4

Molecular Weight: 45.2 kDa

UniProt: Q9UQ80

Pathways: Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades