PRSS22 Protein (His tag)
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- Target See all PRSS22 Proteins
- PRSS22 (Protease, serine, 22 (PRSS22))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This PRSS22 protein is labelled with His tag.
- Purpose
- Recombinant Human PRSS22/BSSP-4 Protein (His Tag)
- Sequence
- Ala33-Ser317
- Characteristics
- Recombinant Human Tryptase epsilon is produced by our Mammalian expression system and the target gene encoding Ala33-Ser317 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PRSS22 Protein
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Protease, serine, 22 (PRSS22) (AA 33-317) protein (His tag)
Crystallography grade PRSS22 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Protease, serine, 22 (PRSS22) (AA 33-306) protein (His tag)Crystallography grade PRSS22 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Protease, serine, 22 (PRSS22) (AA 33-307) protein (His tag)PRSS22 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE. SDS
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, 10 % Glycerol, pH 4.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- PRSS22 (Protease, serine, 22 (PRSS22))
- Alternative Name
- PRSS22/BSSP-4 (PRSS22 Products)
- Synonyms
- BSSP-4 Protein, hBSSP-4 Protein, 4733401N09Rik Protein, SP001LA Protein, protease, serine, 22 Protein, protease, serine 22 Protein, Prss22 Protein, PRSS22 Protein
- Background
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Background: Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung, but scarce in adult lung and expressed at low levels in placenta, pancreas, prostate and thyroid gland. BSSP-4 belongs to the peptidase S1 family and related to trypsin, referentially hydrolyzing substrates after arginine and lysine residues. However, BSSP-4 is less susceptible to inhibition by common trypsin inhibitors such as aprotinin, α1-antitrypsin and secretory leukocyte protease inhibitor. BSSP-4 efficiently converts pro-urokinase- type plasminogen activator to its mature, active form.
Synonym: Brain-Specific Serine Protease 4, BSSP-4, Serine Protease 22, Serine Protease 26, Tryptase Epsilon, PRSS22, BSSP4, PRSS26
- Molecular Weight
- 31.6 kDa
- UniProt
- Q9GZN4
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