POMGNT1 Protein (His tag)
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- Target See all POMGNT1 Proteins
- POMGNT1 (Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase (POMGNT1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This POMGNT1 protein is labelled with His tag.
- Purpose
- Recombinant Human POMGNT1 Protein (His Tag)
- Sequence
- Leu59-Thr660
- Characteristics
- Recombinant Human Protein O-Linked-Mannose beta-1 2-N-Acetylglucosaminyltransferase 1 is produced by our Mammalian expression system and the target gene encoding Leu59-Thr660 is expressed with a 6His tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product POMGNT1 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 8.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- POMGNT1 (Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase (POMGNT1))
- Alternative Name
- POMGNT1 (POMGNT1 Products)
- Synonyms
- POMGNT1 Protein, im:7151461 Protein, zgc:158130 Protein, 0610016I07Rik Protein, 4930467B06Rik Protein, GNTI.2 Protein, GnT I.2 Protein, LGMD2O Protein, MDDGA3 Protein, MDDGB3 Protein, MDDGC3 Protein, MEB Protein, MGAT1.2 Protein, gnT-I.2 Protein, protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) Protein, protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) S homeolog Protein, protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase Protein, POMGNT1 Protein, pomgnt1.S Protein, pomgnt1 Protein, Pomgnt1 Protein
- Background
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Background: Protein O-Linked-Mannose β-1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies type A3 (MDDGA3).
Synonym: Protein O-Linked-Mannose Beta-1,2-N-Acetylglucosaminyltransferase 1, POMGnT1, UDP-GlcNAc:Alpha-D-Mannoside Beta-1,2-N-Acetylglucosaminyltransferase I.2,POMGNT1, MGAT1.2
- Molecular Weight
- 69.3 kDa
- UniProt
- Q8WZA1
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