S100A5 Protein (His tag)

Catalog No. ABIN7320280

Product Details

Target: S100A5 (S100 Calcium Binding Protein A5 (S100A5))

Protein Type: Recombinant

Origin: Mouse

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This S100A5 protein is labelled with His tag.

Purpose: Recombinant Mouse S100A5 Protein (His Tag)

Sequence: Met 1-Lys 93

Characteristics: A DNA sequence encoding the mouse S100A5 (P63084) (Met 1-Lys 93) was expressed, with a polyhistide tag at the N-terminus.

Purity: > 97 % as determined by SDS-PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 20 % glycerol, pH 7.5

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: S100A5 (S100 Calcium Binding Protein A5 (S100A5))

Alternative Name: S100A5 (S100A5 Products)

Synonyms: S100D Protein, S100D9 Protein, S100A5 Protein, S100 calcium binding protein A5 Protein, S100A5 Protein, S100a5 Protein

Background:

Background: S100 protein?is a family of low molecular weight protein found in vertebrates characterized by two?EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is?100 % ?soluble in ammonium sulfate?at neutral? pH . Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the?neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response.?? Protein S100-A5, also known as Protein S-100D, S100 calcium-binding protein A5, S100A5 and S100D, is a member of the S100 family which contains two?EF-hand domains. S100A5 is also a novel member of the EF-hand superfamily of calcium-binding proteins that is poorly characterized at the protein level. It is expressed in very restricted regions of the adult brain. From birth onwards, S100A5 remained a neuronal-specific protein, only located in a subpopulation of neurons in the spiral ganglion.

Synonym: S100D9

Molecular Weight: 12.3 kDa

UniProt: P63084

Pathways: S100 Proteins