SCGB1A1 Protein (His tag)
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- Target See all SCGB1A1 Proteins
- SCGB1A1 (Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This SCGB1A1 protein is labelled with His tag.
- Purpose
- Recombinant Human Uteroglobin/SCGB1A1 Protein (His Tag)
- Sequence
- Glu22-Asn91
- Characteristics
- Recombinant Human Uteroglobin is produced by our Mammalian expression system and the target gene encoding Glu22-Asn91 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SCGB1A1 Protein
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Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1) (Active) protein
SCGB1A1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1) (AA 1-91) protein (GST tag)SCGB1A1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1) (AA 22-91) protein (GST tag)SCGB1A1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1) (AA 22-91) protein (His tag)Crystallography grade SCGB1A1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- SCGB1A1 (Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1))
- Alternative Name
- Uteroglobin/SCGB1A1 (SCGB1A1 Products)
- Synonyms
- CC10 Protein, CC16 Protein, CCPBP Protein, CCSP Protein, UGB Protein, UP-1 Protein, UP1 Protein, UGL Protein, PCB-BP Protein, UG Protein, Utg Protein, PCBB Protein, Ugb Protein, SCGB1A1 Protein, secretoglobin family 1A member 1 Protein, secretoglobin, family 1A, member 1 (uteroglobin) Protein, urinary protein 2 Protein, SCGB1A1 Protein, Scgb1a1 Protein, Rup2 Protein
- Background
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Background: Uteroglobin is a small, non-glycosylated secreted protein of the secretoglobin superfamily. It is produced by the non-ciliated, non-mucous secretory cells that predominate in lung bronchioles (Clara cells), and other non-ciliated epithelia that communicate with the external environment. Expression is induced by steroid hormones such as estrogen, and enhanced by the non-steroid hormone prolactin. Human Uteroglobin cDNA encodes a 21 amino acid (aa) signal sequence and a 70 aa mature protein. The mature protein forms a disulfide-linked head-to-tail homodimer of 16 kDa. This homodimer is thought to form a binding pocket that binds hydrophobic ligands such as phospholipids, progesterone and retinols. Binding of fibronectin to Uteroglobin in the kidney is thought to protect against nephropathy, while binding of the lipocalin-1 receptor has been reported to suppress cancer cell motility and invasion.
Synonym: Uteroglobin, Clara cell phospholipid-binding protein, CCPBP, Clara cells 10 kDa secretory protein, CC10, Secretoglobin family 1A member 1, Urinary protein 1, UP-1, UP1, Urine protein 1, SCGB1A1, CCSP, UGB
- Molecular Weight
- 8.7 kDa
- UniProt
- P11684
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