SERPINB10 Protein (His tag)

Catalog No. ABIN7320212

Product Details

Target: SERPINB10 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 10 (SERPINB10))

Protein Type: Recombinant

Origin: Mouse

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This SERPINB10 protein is labelled with His tag.

Purpose: Recombinant Mouse SerpinB10 Protein (His Tag)

Sequence: Met 1-Pro 397

Characteristics: A DNA sequence encoding the mouse SERPINB10 (Q8K1K6-1) (Met 1-Pro 397) was expressed, with a C-terminal polyhistidine tag.

Purity: > 94 % as determined by SDS-PAGE

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SERPINB10 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 10 (SERPINB10))

Alternative Name: SerpinB10 (SERPINB10 Products)

Synonyms: PI-10 Protein, PI10 Protein, 9830131G07 Protein, BB233602 Protein, Serpinb10-ps Protein, Trespin Protein, MENT-1 Protein, SERPINB10 Protein, pl10 Protein, bomapin Protein, serpin family B member 10 Protein, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 10 B Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 10 L homeolog Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 10 Protein, heterochromatin-associated protein MENT-like Protein, SERPINB10 Protein, Serpinb10 Protein, SERPINB10B Protein, serpinb10.L Protein, LOC100228737 Protein

Background:

Background: Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases (serine protease inhibitors). Over 1000 serpins have been identified. Mouse SerpinB10, also known as Peptidase inhibitor 10, PI-10, Bomapin and SERPINB10, is a nucleus and cytoplasm protein which belongs to the serpin family and Ov-serpin subfamily. SerpinB10 is expressed specifically in the bone marrow. SerpinB10 is a protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. SerpinB10 is a redox-sensitive nuclear serpin that augments proliferation or apoptosis of leukaemia cells, depending on growth factors availability. SerpinB10 may regulate protease activities in the cytoplasm and in the nucleus.

Synonym: 9830131G07;BB233602;Serpinb10-ps

Molecular Weight: 46.5 kDa