SERPINI2 Protein (His tag)

Catalog No. ABIN7319026

Product Details

Target: SERPINI2 (serpin Peptidase Inhibitor, Clade I (Pancpin), Member 2 (SERPINI2))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This SERPINI2 protein is labelled with His tag.

Purpose: Recombinant Human SerpinI2 Protein (His Tag)

Sequence: Ser19-Leu405

Characteristics: Recombinant Human Serine Protease Inhibitor-clade I2 is produced by our Mammalian expression system and the target gene encoding Ser19-Leu405 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SERPINI2 (serpin Peptidase Inhibitor, Clade I (Pancpin), Member 2 (SERPINI2))

Alternative Name: SerpinI2 (SERPINI2 Products)

Synonyms: Spi14 Protein, MEPI Protein, PANCPIN Protein, PI14 Protein, TSA2004 Protein, serpin family I member 2 Protein, serpin peptidase inhibitor, clade I (pancpin), member 2 L homeolog Protein, serpin peptidase inhibitor, clade I (pancpin), member 2 Protein, serine (or cysteine) peptidase inhibitor, clade I, member 2 Protein, SERPINI2 Protein, serpini2.L Protein, Serpini2 Protein

Background:

Background: SERPINI2 is a secreted protein of the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. As protease inhibitors, serpins have an array of functions including regulating blood coagulation, fibrinolysis, the complement pathway, angiogenesis, inflammation, tumor suppression, extracellular matrix remodeling, and cell motility. SERPINI2 is expressed in human tissues including pancreas and adipose tissues. Mutations of human SERPINI2 can directly result in conditions such as acinar cell apoptosis and malabsorption.

Synonym: SERPINI2,Serpin I2,Myoepithelium-derived serine protease inhibitor,Pancreas-specific protein TSA2004,Peptidase inhibitor 14,PI-14,MEPI,PI14,MEPI,PANCPIN,PI14,TSA2004

Molecular Weight: 45.1 kDa

UniProt: O75830