SAA4 Protein (GST tag)

Catalog No. ABIN7317583

Recombinant SAA4 protein expressed in Escherichia coli (E. coli).

Quick Overview for SAA4 Protein (GST tag) (ABIN7317583)

Target: SAA4 (Serum Amyloid A 4 (SAA4))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 93 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This SAA4 protein is labelled with GST tag.

Purpose: Recombinant Human SAA4 Protein (GST Tag)

Sequence: Glu19-Tyr130

Characteristics: A DNA sequence encoding the mature form of human SAA4 (P35542) (Glu19-Tyr130) was fused with the GST tag at the N-terminus.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, 0.5 % Triton X-100, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SAA4 (Serum Amyloid A 4 (SAA4))

Alternative Name: SAA4

Background:

Background: SAA4 is a member of the SAA family.SAA proteins are family of apolipoproteins of high density lipoprotein (HDL). They can be separated into two distinct groups. First group (SAA1, SAA2, and SAA3) consists of acute phase reactant whose expression level increase in the blood in a response to trauma, infection, inflammation, and neoplasia. These acute phase SAAs associates with HDL during inflammation and remodel the HDL particle by displacing Apo-A1. The second distinct group consists of SAA4 and SAA5 which exist as the minor apolipoproteins on HDL, but this group of SAA constitutes more than 90 % of all the SAA during homeostasis, and it is thought to play a role in the normal functioning of the HDL particle. SAA4 is a constitutively expressed protein which expressed only in humans and mice.It is connected almost completely with lipoproteins of the high density range. The physiological function of SAA4 is unknown, and its serum concentration has no association with those of other major apolipoproteins.

Synonym: Serum Amyloid A-4 Protein, Constitutively Expressed Serum Amyloid A Protein, C-SAA, SAA4, CSAA

Molecular Weight: 39.8kDa

UniProt: P35542