SIAE Protein (His tag)
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- Target See all SIAE Proteins
- SIAE (Sialic Acid Acetylesterase (SIAE))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This SIAE protein is labelled with His tag.
- Purpose
- Recombinant Human SIAE Protein (Baculovirus, His Tag)
- Sequence
- Met 1-Lys523
- Characteristics
- A DNA sequence encoding the human SIAE (Met 1-Lys523) (Q9HAT2-1) was expressed, with a C-terminal polyhistidine tag.
- Purity
- > 97 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SIAE Protein
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Sialic Acid Acetylesterase (SIAE) (AA 1-523) protein (GST tag)
SIAE Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Sialic Acid Acetylesterase (SIAE) (AA 24-275) protein (His tag)Crystallography grade SIAE Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sialic Acid Acetylesterase (SIAE) (AA 276-541) protein (His tag)Crystallography grade SIAE Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sialic Acid Acetylesterase (SIAE) (AA 24-523) protein (His tag)Crystallography grade SIAE Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sialic Acid Acetylesterase (SIAE) protein (Myc-DYKDDDDK Tag)SIAE Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- SIAE (Sialic Acid Acetylesterase (SIAE))
- Alternative Name
- SIAE (SIAE Products)
- Synonyms
- MGC68688 Protein, MGC137441 Protein, zgc:56454 Protein, YSG2 Protein, DKFZp469J191 Protein, LSE Protein, Ysg2 Protein, RGD1310431 Protein, AIS6 Protein, CSE-C Protein, CSEC Protein, sialic acid acetylesterase L homeolog Protein, sialic acid acetylesterase Protein, siae.L Protein, SIAE Protein, siae Protein, Siae Protein
- Background
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Background: Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of this enzyme class is N-acyl-O-acetylneuraminate O-acetylhydrolase. Other names in common use include N-acetylneuraminate acetyltransferase, sialate 9(4)-O-acetylesterase, and sialidase. Sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. Defects in Sialate O-acetylesterase are a cause of autoimmune disease type 6 (AIS6). Individuals manifesting susceptibility to autoimmune disease type 6 can suffer from juvenile idiopathic arthritis, rheumatoid arthritis, multiple sclerosis, Sjogren syndrome, systemic lupus erythematosus, type 1 diabetes, ulcerative colitis, and Crohn disease.
Synonym: Sialate O-Acetylesterase, H-Lse, Sialic Acid-Specific 9-O-Acetylesterase, SIAE, YSG2,AIS6,CSE-C,CSEC
- Molecular Weight
- 57.4 kDa
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