SIGLEC9 Protein (His tag)

Catalog No. ABIN7319717

Product Details

Target: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This SIGLEC9 protein is labelled with His tag.

Purpose: Recombinant Human SIGLEC9/CD329 Protein (His Tag)(Active)

Sequence: Gln18-Gly348(Lys100Glu,Ala315Glu)

Characteristics: Recombinant Human SIGLEC9 is produced by our Mammalian expression system and the target gene encoding Gln18-Gly348(Lys100Glu,Ala315Glu) is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. Approximately 93% will adhere after 5-10 mins incubation at 37 °C.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS,2 mMEDTA,ph7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Alternative Name: SIGLEC9/CD329 (SIGLEC9 Products)

Synonyms: CD329 Protein, CDw329 Protein, FOAP-9 Protein, OBBP-LIKE Protein, siglec-9 Protein, siglec9 Protein, sialic acid binding Ig like lectin 9 Protein, sialic acid-binding immunoglobulin-like lectin 9 Protein, SIGLEC9 Protein

Background:

Background: Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils), and found in liver, fetal liver, bone marrow, placenta, spleen and in lower levels in skeletal muscle, fetal brain and so on. It is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It also binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Synonym: Sialic acid-binding Ig-like lectin 9,Siglec-9,CDw329,Protein FOAP-9,SIGLEC9

Molecular Weight: 36.9 kDa

UniProt: Q9Y336