SIRPG Protein (Fc Tag)
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- Target See all SIRPG Proteins
- SIRPG (Signal-Regulatory Protein gamma (SIRPG))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This SIRPG protein is labelled with Fc Tag.
- Purpose
- Recombinant Human SIRP gamma/CD172g Protein (Fc Tag)
- Sequence
- Glu29-Pro360
- Characteristics
- Recombinant Human Signal-Regulatory Protein gamma is produced by our Mammalian expression system and the target gene encoding Glu29-Pro360 is expressed with a Fc tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SIRPG Protein
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Signal-Regulatory Protein gamma (SIRPG) (AA 29-360) protein (His-Avi Tag)
SIRPG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Signal-Regulatory Protein gamma (SIRPG) (AA 29-360) protein (His-Avi Tag,Biotin)SIRPG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Signal-Regulatory Protein gamma (SIRPG) (AA 29-360) protein (His tag)Crystallography grade SIRPG Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Signal-Regulatory Protein gamma (SIRPG) (AA 29-387) protein (rho-1D4 tag)Crystallography grade SIRPG Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Signal-Regulatory Protein gamma (SIRPG) (AA 29-364) protein (Fc Tag)SIRPG Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- SIRPG (Signal-Regulatory Protein gamma (SIRPG))
- Alternative Name
- SIRP gamma/CD172g (SIRPG Products)
- Synonyms
- CD172g Protein, SIRP-B2 Protein, SIRPB2 Protein, SIRPgamma Protein, bA77C3.1 Protein, SIRPG Protein, signal regulatory protein gamma Protein, signal-regulatory protein gamma Protein, SIRPG Protein, LOC716034 Protein, LOC102138723 Protein
- Background
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Background: Signal-Regulatory Protein Gamma (SIRPG) is a member of the signal-regulatory protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRPG is detected in the liver, and at very low levels in the brain, heart, lung, pancreas, kidney, placenta, and skeletal muscle. SIRPG is an immunoglobulin-like cell surface receptor. On binding with CD47, SIRPG mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRPG as receptor-type transmembrane glycoproteins is involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes.
Synonym: Signal-Regulatory Protein Gamma, SIRP-Gamma, CD172 Antigen-Like Family Member B, Signal-Fegulatory Protein Beta-2, SIRP-b2, SIRP-Beta-2, CD172g, SIRPG, SIRPB2
- Molecular Weight
- 63.9 kDa
- UniProt
- Q9P1W8
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