SPOCK3 Protein (His tag)

Catalog No. ABIN7320656

Product Details

Target: SPOCK3 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 3 (SPOCK3))

Protein Type: Recombinant

Origin: Mouse

Source: Human Cells

Purification tag / Conjugate: This SPOCK3 protein is labelled with His tag.

Purpose: Recombinant Mouse Testican-3/SPOCK3 Protein (His Tag)

Sequence: Ala23-Ile436

Characteristics: Recombinant Mouse Testican-3 is produced by our Mammalian expression system and the target gene encoding Ala23-Ile436 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by SDS-PAGE

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SPOCK3 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 3 (SPOCK3))

Alternative Name: Testican-3/SPOCK3 (SPOCK3 Products)

Synonyms: im:7139568 Protein, si:dkey-285b22.1 Protein, HSAJ1454 Protein, TES-3 Protein, TICN3 Protein, Testican-3 Protein, 2900045C01Rik Protein, AI428471 Protein, mKIAA4039 Protein, sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 Protein, SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 Protein, sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3 Protein, spock3 Protein, SPOCK3 Protein, Spock3 Protein

Background:

Background: Testican3, also called SPOCK3, is a secreted protein and make up a family of extracellular heparan/chondroitin sulfate proteoglycans. It contains 1 Kazal-like domain and 1 thyroglobulin type-1 domain. Testican3 contain inhibitory regions in several domains targeted to different classes of protease, and in some cases may act as protease inhibitors. In addition to their presence in testis, testicans are enriched in brain and have been shown to regulate neuronal attachment and outgrowth. It may participate in diverse steps of neurogenesis and Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. It also may interfere with tumor invasion.

Synonym: Testican-3,Spock3

Molecular Weight: 47.9 kDa

Pathways: Glycosaminoglycan Metabolic Process