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ST8SIA1 Protein (His tag)

ST8SIA1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319204
  • Target See all ST8SIA1 Proteins
    ST8SIA1 (ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 1 (ST8SIA1))
    Protein Type
    Recombinant
    Origin
    • 4
    • 2
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This ST8SIA1 protein is labelled with His tag.
    Purpose
    Recombinant Human ST8SIA1 Protein (His Tag)
    Sequence
    Tyr49-Ser356
    Characteristics
    Recombinant Human alpha-N-Acetylneuraminide alpha-2,8-Sialyltransferase is produced by our Mammalian expression system and the target gene encoding Tyr49-Ser356 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ST8SIA1 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    ST8SIA1 (ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 1 (ST8SIA1))
    Alternative Name
    ST8SIA1 (ST8SIA1 Products)
    Synonyms
    SIAL-T2 Protein, Xlgd3 Protein, siat8 Protein, siat8a Protein, st8sial Protein, st8siaI Protein, ST8SIA1 Protein, St8sia1 Protein, GD3S Protein, SIAT8 Protein, SIAT8-A Protein, SIAT8A Protein, ST8SiaI Protein, 9330109E03Rik Protein, Sia-T Protein, Siat8 Protein, Siat8a Protein, ST8SIA-IV Protein, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 Protein, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 L homeolog Protein, ST8SIA1 Protein, st8sia1.L Protein, st8sia1 Protein, St8sia1 Protein
    Background

    Background: α-N-Acetylneuraminide α-2,8-Sialyltransferase (ST8SIA1) belongs to the glycosyltransferase 29 family. ST8SIA1 is a sialytransferase that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce GD3 and GT3. ST8SIA1 is highly expressed in melanoma cell lines, adult and fetal brain, low expressed in adult and fetal lung. ST8SIA1 may act as a type II transmembrane protein with a short N-termianl cytoplasmic domain and a single-pass transmembrane domain folowed by an enzymatic domain in the lument of the Golgi apparatus.

    Synonym: Alpha-N-Acetylneuraminide Alpha-2,8-Sialyltransferase, Alpha-2,8-Sialyltransferase 8A, Ganglioside GD3 Synthase, Ganglioside GT3 Synthase, Sialyltransferase 8A, SIAT8-A, Sialytransferase St8Sia I, ST8SiaI, ST8SIA1, SIAT8, SIAT8A

    Molecular Weight
    36.2 kDa
    UniProt
    Q92185
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