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SENP8 Protein (AA 1-311) (His tag)

SENP8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319011
  • Target See all SENP8 Proteins
    SENP8 (SUMO/sentrin Specific Peptidase Family Member 8 (SENP8))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-311
    Origin
    • 7
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SENP8 protein is labelled with His tag.
    Purpose
    Recombinant Human SENP8 Protein (His Tag)
    Sequence
    Met 1-Lys212
    Characteristics
    Recombinant Human Sentrin-Specific Protease 8 is produced by our E.coli expression system and the target gene encoding Met1-Lys212 is expressed with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product SENP8 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    SENP8 (SUMO/sentrin Specific Peptidase Family Member 8 (SENP8))
    Alternative Name
    SENP8 (SENP8 Products)
    Synonyms
    den1 Protein, nedp1 Protein, prsc2 Protein, MGC84956 Protein, F15L12.8 Protein, F15L12_8 Protein, 9130010J17Rik Protein, AU020827 Protein, Den1 Protein, Nedp1 Protein, Prsc2 Protein, DEN1 Protein, NEDP1 Protein, PRSC2 Protein, SUMO/sentrin peptidase family member, NEDD8 specific L homeolog Protein, Cysteine proteinases superfamily protein Protein, SUMO/sentrin specific peptidase 8 Protein, SUMO/sentrin peptidase family member, NEDD8 specific Protein, senp8.L Protein, AT5G60190 Protein, Senp8 Protein, SENP8 Protein
    Background

    Background: Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins.

    Synonym: Sentrin-Specific Protease 8, Deneddylase-1, NEDD8-Specific Protease 1, Protease Cysteine 2, Sentrin/SUMO-Specific Protease SENP8, SENP8, DEN1, NEDP1, PRSC2

    Molecular Weight
    26.2 kDa
    UniProt
    Q96LD8
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