SENP7 Protein (His tag)
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- Target See all SENP7 Proteins
- SENP7 (SUMO1/sentrin Specific Protease 7 (SENP7))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SENP7 protein is labelled with His tag.
- Purpose
- Recombinant Human SENP7 Protein (His Tag)
- Sequence
- Met695-Ala864
- Characteristics
- Recombinant Human Sentrin-Specific Protease 7 is produced by our E.coli expression system and the target gene encoding Met695-Ala864 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SENP7 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 5 % Glycerol, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- SENP7 (SUMO1/sentrin Specific Protease 7 (SENP7))
- Alternative Name
- SENP7 (SENP7 Products)
- Synonyms
- SENP7 Protein, 2410152H17Rik Protein, 2810413I22Rik Protein, 2900036C23Rik Protein, 6030449K19Rik Protein, AI790676 Protein, mKIAA1707 Protein, SUMO1/sentrin specific peptidase 7 Protein, SENP7 Protein, Senp7 Protein
- Background
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Background: Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1.
Synonym: Sentrin-Specific Protease 7, SUMO-1-Specific Protease 2, Sentrin/SUMO-Specific Protease SENP7, SENP7, KIAA1707, SSP2, SUSP2
- Molecular Weight
- 27.3 kDa
- UniProt
- Q9BQF6
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