SDCBP Protein (His tag)

Catalog No. ABIN7319068

Product Details

Target: SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SDCBP protein is labelled with His tag.

Purpose: Recombinant Human Syntenin-1/SDCBP Protein (His Tag)

Sequence: Ser2-Val298

Characteristics: Recombinant Human Syndecan-binding protein 1 is produced by our E.coli expression system and the target gene encoding Ser2-Val298 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))

Alternative Name: Syntenin-1/SDCBP (SDCBP Products)

Synonyms: MDA-9 Protein, ST1 Protein, SYCL Protein, TACIP18 Protein, Sycl Protein, syntenin-1 Protein, mda-9 Protein, st1 Protein, sycl Protein, tacip18 Protein, MGC81274 Protein, syntenin Protein, wu:fc51c03 Protein, wu:fk31e01 Protein, zgc:55679 Protein, zgc:77716 Protein, sb:eu862 Protein, si:dkey-235k4.1 Protein, syndecan binding protein Protein, syndecan binding protein L homeolog Protein, syndecan binding protein (syntenin) 2 Protein, syndecan binding protein (syntenin) Protein, SDCBP Protein, Sdcbp Protein, sdcbp.L Protein, LOC732879 Protein, sdcbp2 Protein, sdcbp Protein

Background:

Background: Syntenin-1 is a molecule linking syndecan-mediated signaling to the cytoskeleton. Syntenin-1 is primarily localized to membrane-associated adherens junctions and focal adhesions but also found at the endoplasmic reticulum and nucleus. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. Syntenin-1 may affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. It seems to function as an adapter protein, in adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Syntenin-1 seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA) and play a role in vesicular trafficking.

Synonym: Syntenin-1, Melanoma differentiation-associated protein 9, Pro-TGF-alpha cytoplasmic domain-interacting protein 18, Scaffold protein Pbp1,Syndecan-binding protein 1, SDCBP, MDA9, SYCL,

Molecular Weight: 33.5 kDa

UniProt: O00560