STXBP3 Protein (GST tag,His tag)
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- Target See all STXBP3 Proteins
- STXBP3 (Syntaxin Binding Protein 3 (STXBP3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This STXBP3 protein is labelled with GST tag,His tag.
- Purpose
- Recombinant Human STXBP3/UNC-18C Protein (His & GST Tag)
- Sequence
- Met 1-Glu 592
- Characteristics
- A DNA sequence encoding the human STXBP3 (O00186-1) (Met 1-Glu 592) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- Purity
- > 82 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product STXBP3 Protein
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Syntaxin Binding Protein 3 (STXBP3) (AA 1-592) protein (GST tag)
STXBP3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Syntaxin Binding Protein 3 (STXBP3) (AA 493-592) protein (GST tag)STXBP3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Syntaxin Binding Protein 3 (STXBP3) (AA 1-592) protein (Strep Tag)Crystallography grade STXBP3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Syntaxin Binding Protein 3 (STXBP3) (AA 1-592) protein (Strep Tag)Crystallography grade STXBP3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Syntaxin Binding Protein 3 (STXBP3) protein (Myc-DYKDDDDK Tag)STXBP3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.5, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- STXBP3 (Syntaxin Binding Protein 3 (STXBP3))
- Alternative Name
- STXBP3/UNC-18C (STXBP3 Products)
- Synonyms
- MUNC18-3 Protein, MUNC18C Protein, PSP Protein, UNC-18C Protein, Munc18-c Protein, wu:fb71h06 Protein, zgc:63761 Protein, stxbp3 Protein, MGC115462 Protein, Munc-18c Protein, Stxbp3 Protein, Sxtbp3 Protein, Unc18-3 Protein, syntaxin binding protein 3 Protein, syntaxin binding protein 3 L homeolog Protein, STXBP3 Protein, Stxbp3 Protein, stxbp3 Protein, stxbp3.L Protein
- Background
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Background: Syntaxin-binding protein 3, also known as Platelet Sec1 protein, Protein unc-18 homolog 3, Protein unc-18 homolog C, Unc-18C, Unc18-3 and STXBP3, is a cytoplasm protein which belongs to the STXBP/unc-18/SEC1 family. STXBP3 is expressed in cells that exhibit granule exocytosis, such as neutrophils, mast cells, platelets and endothelial cells. STXBP3, together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking / fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. STXBP3 participates in the consolidation and secretion of secondary and tertiary granules. STXBP3 contains one SEC1 domain. Phosphorylation at Ser129 may stimulate granule release. Human STXBP3 shares 90% aa identity with mouse STXBP3. STXBP3 interacts with DOC2B; the interaction is direct, occurs at the cell membrane, excludes interaction with STX4 and regulates glucose-stimulated insulin secretion. Interacts with STX4.
Synonym: MUNC18-3;MUNC18C;PSP;UNC-18C
- Molecular Weight
- 95.6 kDa
- Pathways
- Hormone Transport
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