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TAO Kinase 3 Protein (TAOK3) (AA 1-411) (GST tag,His tag)

TAOK3 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 92 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7317073
  • Target See all TAO Kinase 3 (TAOK3) Proteins
    TAO Kinase 3 (TAOK3)
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 1-411
    Origin
    • 7
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This TAO Kinase 3 protein is labelled with GST tag,His tag.
    Purpose
    Recombinant Human TAOK3/JIK/MAP3K18 Protein (aa 1-411, His & GST Tag)(Active)
    Sequence
    Met 1-Asp 411
    Characteristics
    A DNA sequence encoding the amino acids (Met 1-Asp 411) of human TAOK3 (Q9H2K8-1) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
    Purity
    > 92 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    The specific activity was determined to be 10 nmol/min/mg using synthetic PKCtide peptide (ERMRPRKRQGSVRRRV) as substrate.
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    Discover our top product TAOK3 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as sterile 20 mM Tris, 500 mM NaCl, 3 mM GSH, pH 7.4, 10 % glycerol
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    TAO Kinase 3 (TAOK3)
    Alternative Name
    TAOK3/JIK/MAP3K18 (TAOK3 Products)
    Synonyms
    TAOK3 Protein, JIK Protein, si:ch1073-179p4.1 Protein, taok3 Protein, DPK Protein, MAP3K18 Protein, 2900006A08Rik Protein, A130052D22 Protein, A430105I05Rik Protein, TAO kinase 3 Protein, TAO kinase 3a Protein, TAOK3 Protein, taok3a Protein, taok3 Protein, Taok3 Protein
    Background

    Background: Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK / SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, Thousand and one amino acid protein 3, JIK, TAOK3 and MAP3K18, is cytoplasm and peripheral membrane protein which belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. Protein kinases are pivotal regulators of cell signaling that modulate each other's functions and activities through site-specific phosphorylation events. TAOK3 / JIK contains one protein kinase domain. TAOK3 / JIK is ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver. TAOK3 / JIK inhibits the basal activity of Jun kinase. It is negatively regulated by epidermal growth factor (EGF). When overexpressed, TAOK3 / JIK may activate ERK1 / ERK2 and JNK / SAPK.

    Synonym: DPK;JIK;MAP3K18

    Molecular Weight
    74.3 kDa
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