TXNL4A Protein (His tag)
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- Target See all TXNL4A Proteins
- TXNL4A (Thioredoxin-Like 4A (TXNL4A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TXNL4A protein is labelled with His tag.
- Purpose
- Recombinant Human DIM1/TXNL4A Protein (His Tag)
- Sequence
- Met 1-Tyr 142
- Characteristics
- A DNA sequence encoding the human TXNL4A (P83876) (Met 1-Tyr 142) was expressed, with a polyhistidine tag at the N-terminus.
- Purity
- > 94 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product TXNL4A Protein
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Thioredoxin-Like 4A (TXNL4A) (AA 1-142) protein (His tag)
TXNL4A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Thioredoxin-Like 4A (TXNL4A) (AA 1-142) protein (GST tag)TXNL4A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Thioredoxin-Like 4A (TXNL4A) (AA 1-142) protein (Strep Tag)Crystallography grade TXNL4A Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Thioredoxin-Like 4A (TXNL4A) protein (Myc-DYKDDDDK Tag)TXNL4A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 50 mM Tris, 150 mM NaCl, pH 8.0
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- TXNL4A (Thioredoxin-Like 4A (TXNL4A))
- Alternative Name
- DIM1/TXNL4A (TXNL4A Products)
- Synonyms
- Txnl4 Protein, TXNL4A Protein, txnl4a Protein, dim1 Protein, MGC85128 Protein, DIB1 Protein, DIM1 Protein, HsT161 Protein, SNRNP15 Protein, TXNL4 Protein, U5-15kD Protein, D18Wsu98e Protein, Dim1 Protein, ENSMUSG00000057130 Protein, U5-15kDa Protein, thioredoxin-like 4A Protein, thioredoxin like 4A Protein, thioredoxin like 4A S homeolog Protein, Txnl4a Protein, TXNL4A Protein, txnl4a Protein, LOC664328 Protein, txnl4a.S Protein
- Background
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Background: DIM1, also known as TXNL4A, is a member of the Dim protein family. The Dim protein family is composed of two classes, DIM1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their role in cell cycle progression and have been found to interact with Prp6, an essential component of the spliceosome, which forms the bridge of U4/U6.U5-tri-snRNP. In spite of their biological and structural similarities, DIM1 and Dim2 proteins differ in many aspects. DIM1 bears distinctive structural motifs responsible for its interaction with other spliceosome components. Dim2 forms homodimers and contains specific domains required for its interactions with partners. This originality suggests that although both proteins are involved in pre-mRNA splicing, they are likely to be involved in different biological pathways. DIM1 interacts with HNRPF, HNRPH2, NEDD9/HEF1 and PQBP1/NPW38. It plays an essential role in pre-mRNA splicing.
Synonym: BMKS,DIB1,DIM1,SNRNP15,TXNL4,U5-15kD
- Molecular Weight
- 18.6kDa
- UniProt
- P83876
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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