TLK1 Protein (GST tag,His tag)
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- Target See all TLK1 Proteins
- TLK1 (Tousled-Like Kinase 1 (TLK1))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This TLK1 protein is labelled with GST tag,His tag.
- Purpose
- Recombinant Human TLK1/PKU-beta Protein (His & GST Tag)(Active)
- Sequence
- Met 1-Tyr 766
- Characteristics
- A DNA sequence encoding the human TLK1 isoform 1 (Q9UKI8-1) (Met 1-Tyr 766) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- Purity
- > 88 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- The specific activity was determined to be 1.6 nmol/min/mg using Histone H3 protein as substrate.
- Top Product
- Discover our top product TLK1 Protein
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Tousled-Like Kinase 1 (TLK1) (AA 1-766) (Active) protein (GST tag)
TLK1 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active
Tousled-Like Kinase 1 (TLK1) (AA 111-230) protein (GST tag)TLK1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Tousled-Like Kinase 1 (TLK1) (AA 1-766) protein (Strep Tag)Crystallography grade TLK1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Tousled-Like Kinase 1 (TLK1) (AA 1-766) protein (Strep Tag)Crystallography grade TLK1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Tousled-Like Kinase 1 (TLK1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TLK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- TLK1 (Tousled-Like Kinase 1 (TLK1))
- Alternative Name
- TLK1/PKU-beta (TLK1 Products)
- Synonyms
- PKU-beta Protein, 4930545J15Rik Protein, fe11e12 Protein, si:dkey-251e16.4 Protein, tlk1 Protein, wu:fe11e12 Protein, TLK1 Protein, fb76h12 Protein, si:dkey-88m1.1 Protein, wu:fb76h12 Protein, DKFZp459L163 Protein, tousled like kinase 1 Protein, tousled-like kinase 1 Protein, tousled-like kinase 1b Protein, tousled like kinase 1 like Protein, serine/threonine-protein kinase TOUSLED Protein, tousled-like kinase 1a Protein, Serine/threonine-protein kinase tousled-like 1 Protein, TLK1 Protein, Tlk1 Protein, tlk1b Protein, TLK1L Protein, LOC542181 Protein, tlk1a Protein, tlk1 Protein, tlk-1 Protein
- Background
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Background: The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.
Synonym: KIAA0137,PKU-beta
- Molecular Weight
- 114 kDa
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