TGFBI Protein (His tag)
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- Target See all TGFBI Proteins
- TGFBI (Transforming Growth Factor, beta-Induced, 68kDa (TGFBI))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TGFBI protein is labelled with His tag.
- Purpose
- Recombinant Human TGFBI/BIGH3 Protein (His Tag)
- Sequence
- Met 1-His 683
- Characteristics
- A DNA sequence encoding the extracellular domain of human beta IG-H3 (NP_000349.1) precursor (Met 1-His 683) was expressed, fused with a polyhistidine tag at the C-terminus.
- Purity
- > 75 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TGFBI Protein
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Transforming Growth Factor, beta-Induced, 68kDa (TGFBI) (AA 502-683) protein
TGFBI Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS
Transforming Growth Factor, beta-Induced, 68kDa (TGFBI) (AA 502-636) proteinTGFBI Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS
Transforming Growth Factor, beta-Induced, 68kDa (TGFBI) (AA 481-580) protein (GST tag)TGFBI Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Transforming Growth Factor, beta-Induced, 68kDa (TGFBI) (AA 24-683) protein (His tag)Crystallography grade TGFBI Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Transforming Growth Factor, beta-Induced, 68kDa (TGFBI) (AA 24-683) protein (His tag)Crystallography grade TGFBI Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- TGFBI (Transforming Growth Factor, beta-Induced, 68kDa (TGFBI))
- Alternative Name
- TGFBI/BIGH3 (TGFBI Products)
- Synonyms
- TGFBI Protein, BIGH3 Protein, CDB1 Protein, CDG2 Protein, CDGG1 Protein, CSD Protein, CSD1 Protein, CSD2 Protein, CSD3 Protein, EBMD Protein, LCD1 Protein, 68kDa Protein, AI181842 Protein, AI747162 Protein, Beta-ig Protein, big-h3 Protein, Big-h3 Protein, MP70 Protein, MP78 Protein, hm:zeh0933 Protein, wu:fa13f05 Protein, zgc:110495 Protein, transforming growth factor beta induced Protein, transforming growth factor, beta induced Protein, transforming growth factor, beta-induced Protein, TGFBI Protein, Tgfbi Protein, tgfbi Protein
- Background
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Background: TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in TGFBI are associated with multiple types of corneal dystrophy. TGFBI can bind to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, TGFBI may be involved in endochondral bone formation. Loss of the TGFBI is sufficient to induce specific resistance.
Synonym: BIGH3,CDB1,CDG2,CDGG1,CSD,CSD1,CSD2,CSD3,EBMD,LCD1
- Molecular Weight
- 74 kDa
- NCBI Accession
- NP_000349
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