TSC22D1 Protein (His tag)
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- Target See all TSC22D1 Proteins
- TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TSC22D1 protein is labelled with His tag.
- Purpose
- Recombinant Human TSC22D1 Protein (His Tag)
- Sequence
- Met 1-Ala 144
- Characteristics
- A DNA sequence encoding the human TSC22D1 isoform 2 (Q15714-2) (Met 1-Ala 144) was expressed, with a polyhistidine tag at the N-terminus.
- Purity
- > 92 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product TSC22D1 Protein
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TSC22 Domain Family, Member 1 (TSC22D1) (AA 1-144) protein (GST tag)
TSC22D1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
TSC22 Domain Family, Member 1 (TSC22D1) (AA 1-1073) protein (Strep Tag)Crystallography grade TSC22D1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
TSC22 Domain Family, Member 1 (TSC22D1) (AA 1-1077) protein (Strep Tag)Crystallography grade TSC22D1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))
- Alternative Name
- TSC22D1 (TSC22D1 Products)
- Synonyms
- Ptg-2 Protein, TGFB1I4 Protein, TSC22 Protein, AA589566 Protein, AW105905 Protein, Egr5 Protein, TSC-22 Protein, Tgfb1i4 Protein, Tsc Protein, Tsc22 Protein, tsc22 Protein, TS22A Protein, fj34d05 Protein, wu:fj34d05 Protein, zgc:65869 Protein, zgc:85857 Protein, TSC22D1 Protein, tsc22d1 Protein, MGC69210 Protein, MGC186361 Protein, DKFZp459J163 Protein, TSC22 domain family member 1 Protein, TSC22 domain family, member 1 Protein, TSC22 domain family member 1 L homeolog Protein, TSC22D1 Protein, Tsc22d1 Protein, tsc22d1.L Protein, tsc22d1 Protein
- Background
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Background: TSC22 domain family, member 1 (TSC22D1) is one of the TGF-beta-stimulated clone-22 (TSC-22). TSC-22 was reported to be a differentiation-inducing factor which negatively regulates the growth of salivary gland cancer cells. TSC22D1, which encodes transforming growth factor beta-stimulated clone 22 (TSC-22), is thought to be a tumor suppressor because its expression is lost in many glioblastoma, salivary gland, and prostate cancers. TSC-22 is the founding member of the TSC-22/DIP/Bun family of leucine zipper transcription factors. TSC-22 may play an important role in maintaining the differentiated phenotype in salivary gland tumors, and may be a possible target of leukemia therapy. TSC22D1 forms homodimers via its conserved leucine zipper domain and heterodimerizes with TSC22D4. TSC22D1 has transcriptional repressor activity.
Synonym: Ptg-2,TGFB1I4,TSC22
- Molecular Weight
- 17.2 kDa
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