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Ube2t Protein (His tag)

Ube2t Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7198597
  • Target See all Ube2t Proteins
    Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Ube2t protein is labelled with His tag.
    Purpose
    Recombinant Human UBE2T Protein (His Tag)
    Sequence
    Met 1-Val197
    Characteristics
    A DNA sequence encoding the human UBE2T (Q9NPD8) (Met1-Val197) was fused with a polyhistidine tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, 30 % glycerol, 0.1 % Tween 20, 0.4 mM Chaps, pH 7.5
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
    Alternative Name
    UBE2T (Ube2t Products)
    Synonyms
    PIG50 Protein, UBE2T Protein, 2700084L22Rik Protein, C80607 Protein, RGD1310816 Protein, hspc150 Protein, wu:fj86h11 Protein, zgc:153687 Protein, ubiquitin conjugating enzyme E2 T Protein, ubiquitin-conjugating enzyme E2T Protein, ubiquitin conjugating enzyme E2T S homeolog Protein, ubiquitin-conjugating enzyme E2T (putative) Protein, UBE2T Protein, Ube2t Protein, ube2t.S Protein, ube2t Protein
    Background

    Background: Ube2T is the E2 ubiquitin-conjugating enzyme of the Fanconi anemia DNA repair pathway and it is overexpressed in several cancers, representing an attractive target for the development of inhibitors. Notably, UBE2T locates at 1q32.1, and the gain of 1q is frequently observed in a variety of cancers. For instance, UBE2T serves an important role in the growth of bladder cancer cells, and may be considered as a potential biomarker and therapeutic target for bladder cancer.

    Synonym: Ubiquitin-Conjugating Enzyme E2 T, Cell Proliferation-Inducing Gene 50 Protein, Ubiquitin Carrier Protein T, Ubiquitin-Protein Ligase T, UBE2T

    Molecular Weight
    23.9 kDa
    UniProt
    Q9NPD8
    Pathways
    Chromatin Binding
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