B3GNT2 Protein (Fc Tag)

Catalog No. ABIN7317561

Product Details

Target: B3GNT2 (UDP-GlcNAc:BetaGal beta-1,3-N-Acetylglucosaminyltransferase 2 (B3GNT2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This B3GNT2 protein is labelled with Fc Tag.

Purpose: Recombinant Human B3GNT2 Protein (Fc Tag)

Sequence: Lys29-Cys397

Characteristics: A DNA sequence encoding the human B3GNT2 (Q9NY97-1) (Lys29-Cys397) was expressed,with the fused Fc region of human IgG1 at the N-terminus.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: B3GNT2 (UDP-GlcNAc:BetaGal beta-1,3-N-Acetylglucosaminyltransferase 2 (B3GNT2))

Alternative Name: B3GNT2 (B3GNT2 Products)

Synonyms: B3GN-T2 Protein, B3GNT Protein, B3GNT-2 Protein, B3GNT1 Protein, BETA3GNT Protein, BGNT2 Protein, BGnT-2 Protein, AA408337 Protein, AA409404 Protein, AW260308 Protein, B3Galt6 Protein, B3gnt1 Protein, BGnT-1 Protein, BGnT1 Protein, BGnT2 Protein, Beta3gnt Protein, MGC81185 Protein, B3GNT2 Protein, MGC179257 Protein, ssp5 Protein, wu:fa55h04 Protein, wu:fc39c01 Protein, zgc:113947 Protein, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Protein, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 L homeolog Protein, beta-1,4-glucuronyltransferase 1 Protein, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b Protein, B3GNT2 Protein, B3gnt2 Protein, b3gnt2.L Protein, B4GAT1 Protein, b3gnt2b Protein, b3gnt2 Protein

Background:

Background: B3GNT2 belongs to the beta-1,3-N-acetylglucosaminyltransferase family. It is a type II transmembrane protein which prefers the substrate of lacto-N-neotetraose. Alternative splicing produced 2 isoforms of the human protein. B3GNT2 catalyzes the initiation and elongation of poly-N- acetyllactosamine chains. Enzymatic activities of some glycosyltransferases are markedly increased via complex formation with other transferases or cofactor proteins. B3GNT2 and beta3Gn-T8 can form a heterodimer in vitro and that the complex exhibits much higher enzymatic activity than either enzyme alone. It is found that up-regulation of beta3Gn-T8 in differentiated HL-60 cells may increases poly-N-acetyllactosamine chains by activating intrinsic B3GNT2.

Synonym: B3GN-T2,B3GNT,B3GNT-2,B3GNT1,BETA3GNT,BGnT-2,BGNT2

Molecular Weight: 71.2 kDa

Pathways: Glycosaminoglycan Metabolic Process