UPRT Protein (His tag)

Catalog No. ABIN7319160

Product Details

Target: UPRT (Uracil phosphoribosyltransferase (FUR1) Homolog (UPRT))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This UPRT protein is labelled with His tag.

Purpose: Recombinant Human UPRT Protein (His Tag)

Sequence: Met 1-Asp309

Characteristics: Recombinant Human Uracil phosphoribosyltransferase homolog is produced by our E.coli expression system and the target gene encoding Met1-Asp309 is expressed with a 6His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl pH 8.0.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: UPRT (Uracil phosphoribosyltransferase (FUR1) Homolog (UPRT))

Alternative Name: UPRT (UPRT Products)

Synonyms: Gm774 Protein, FUR1 Protein, UPP Protein, uracil phosphoribosyltransferase Protein, uracil phosphoribosyltransferase homolog Protein, Uprt Protein, UPRT Protein

Background:

Background: UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. UPRT is a potential target for rational design of drugs to treat parasitic infections and cancer

Synonym: Uracil phosphoribosyltransferase homolog, UPP, FUR1, UPRT

Molecular Weight: 35.9 kDa

UniProt: Q96BW1

Pathways: Ribonucleoside Biosynthetic Process