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PROC Protein (His tag)

PROC Origin: Human Host: HEK-293 Cells Recombinant (79+20.5) % as determined by reducing SDS-PAGE.
Catalog No. ABIN7198701
  • Target See all PROC Proteins
    PROC (Vitamin K-dependent protein C (PROC))
    Protein Type
    Recombinant
    Origin
    • 11
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 9
    • 9
    • 5
    • 3
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PROC protein is labelled with His tag.
    Purpose
    Recombinant Human PROC1/Protein C/PROC Protein (His Tag)
    Sequence
    Met 1-Pro461
    Characteristics
    A DNA sequence encoding the human PROC (P04070) (Met1-Pro461) was expressed with a C-terminal polyhistidine tag.
    Purity
    (79+20.5) % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product PROC Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    PROC (Vitamin K-dependent protein C (PROC))
    Alternative Name
    PROC1 (PROC Products)
    Synonyms
    proc Protein, si:ch1073-188c16.3 Protein, zgc:63987 Protein, PROC Protein, APC Protein, PC Protein, PROC1 Protein, THPH3 Protein, THPH4 Protein, proc1 Protein, MGC64425 Protein, PA Protein, protein C, inactivator of coagulation factors Va and VIIIa Protein, protein C (inactivator of coagulation factors Va and VIIIa), a Protein, protein C (inactivator of coagulation factors Va and VIIIa) Protein, protein C, inactivator of coagulation factors Va and VIIIa S homeolog Protein, vitamin K-dependent protein C Protein, prosaposin Protein, protein C Protein, proline rich protein HaeIII subfamily 1 Protein, PROC Protein, proca Protein, proc.S Protein, proc Protein, CpipJ_CPIJ000393 Protein, CpipJ_CPIJ002754 Protein, CpipJ_CPIJ003717 Protein, CpipJ_CPIJ003718 Protein, CpipJ_CPIJ014440 Protein, CpipJ_CPIJ018032 Protein, CpipJ_CPIJ018737 Protein, PSAP Protein, Proc Protein, PRH1 Protein
    Target Type
    Viral Protein
    Background

    Background: CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.

    Synonym: APC,PC,PROC,PROC1,THPH3,THPH4

    Molecular Weight
    51.5 kDa
    UniProt
    P04070
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