COL3A1 Protein (His tag)
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- Target See all COL3A1 Proteins
- COL3A1 (Collagen, Type III, alpha 1 (COL3A1))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This COL3A1 protein is labelled with His tag.
- Purpose
- Recombinant Mouse Collagen α-1(III) Chain/COL3A1 Protein (His Tag)
- Sequence
- Gln155-Gly1219
- Characteristics
- Recombinant Mouse Collagen alpha-1(III) chain is produced by our Mammalian expression system and the target gene encoding Gln155-Gly1219 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product COL3A1 Protein
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- Comment
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130 kDa
- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc,150 mM NaCl, pH 4.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- COL3A1 (Collagen, Type III, alpha 1 (COL3A1))
- Alternative Name
- COL3A1 (COL3A1 Products)
- Synonyms
- EDS4A Protein, AW550625 Protein, Col3a-1 Protein, MMS10-W Protein, Ms10w Protein, mKIAA4231 Protein, col3a1 Protein, collagen type III alpha 1 chain Protein, collagen, type III, alpha 1 Protein, collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) S homeolog Protein, COL3A1 Protein, Col3a1 Protein, col3a1 Protein, col3a1.S Protein
- Background
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Background: Collagen alpha-1(III) chain(Col3a1) is a secreted protein and belongs to the fibrillar collagen family.It contains 1 fibrillar collagen NC1 domain and 1 VWFC domain. Collagen alpha-1(III) chain is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I collagen. The COL3A1 gene produces the components of type III collagen, called pro-alpha1(III) chains. Three copies of this chain combine to make a molecule of type III procollagen. These triple-stranded, rope-like procollagen molecules must be processed by enzymes outside the cell to remove extra protein segments from their ends. Once these molecules are processed, the collagen molecules arrange themselves into long, thin fibrils. Within these fibrils, the individual collagen molecules are cross-linked to one another. These cross-links result in the formation of very strong mature type III collagen fibrils, which are found in the spaces around cells.
Synonym: Collagen alpha-1(III) chain,Col3a1
- Molecular Weight
- 96.6 kDa
- UniProt
- P08121
- Pathways
- Autophagy, Growth Factor Binding
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