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COL3A1 Protein (His tag)

COL3A1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7320493
  • Target See all COL3A1 Proteins
    COL3A1 (Collagen, Type III, alpha 1 (COL3A1))
    Protein Type
    Recombinant
    Origin
    • 6
    • 4
    • 2
    Mouse
    Source
    • 6
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This COL3A1 protein is labelled with His tag.
    Purpose
    Recombinant Mouse Collagen α-1(III) Chain/COL3A1 Protein (His Tag)
    Sequence
    Gln155-Gly1219
    Characteristics
    Recombinant Mouse Collagen alpha-1(III) chain is produced by our Mammalian expression system and the target gene encoding Gln155-Gly1219 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product COL3A1 Protein
  • Comment

    130 kDa

    Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc,150 mM NaCl, pH 4.5.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    COL3A1 (Collagen, Type III, alpha 1 (COL3A1))
    Alternative Name
    COL3A1 (COL3A1 Products)
    Synonyms
    EDS4A Protein, AW550625 Protein, Col3a-1 Protein, MMS10-W Protein, Ms10w Protein, mKIAA4231 Protein, col3a1 Protein, collagen type III alpha 1 chain Protein, collagen, type III, alpha 1 Protein, collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) S homeolog Protein, COL3A1 Protein, Col3a1 Protein, col3a1 Protein, col3a1.S Protein
    Background

    Background: Collagen alpha-1(III) chain(Col3a1) is a secreted protein and belongs to the fibrillar collagen family.It contains 1 fibrillar collagen NC1 domain and 1 VWFC domain. Collagen alpha-1(III) chain is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I collagen. The COL3A1 gene produces the components of type III collagen, called pro-alpha1(III) chains. Three copies of this chain combine to make a molecule of type III procollagen. These triple-stranded, rope-like procollagen molecules must be processed by enzymes outside the cell to remove extra protein segments from their ends. Once these molecules are processed, the collagen molecules arrange themselves into long, thin fibrils. Within these fibrils, the individual collagen molecules are cross-linked to one another. These cross-links result in the formation of very strong mature type III collagen fibrils, which are found in the spaces around cells.

    Synonym: Collagen alpha-1(III) chain,Col3a1

    Molecular Weight
    96.6 kDa
    UniProt
    P08121
    Pathways
    Autophagy, Growth Factor Binding
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