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BTN3A1 Protein (Biotin)

This Recombinant BTN3A1 protein is produced in Human Cells.
Catalog No. ABIN7319892

Quick Overview for BTN3A1 Protein (Biotin) (ABIN7319892)

Target

See all BTN3A1 Proteins
BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))

Protein Type

Recombinant

Origin

  • 15
  • 3
Human

Source

  • 12
  • 3
  • 2
  • 1
Human Cells

Purity

>90 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This BTN3A1 protein is labelled with Biotin.

    Purpose

    Recombinant Human Butyrophilin Subfamily 3 Member A1/BTN3A1 (C-Fc-Avi) Biotinylated

    Sequence

    Gln30-Gly254

    Characteristics

    Biotinylated Recombinant Human Butyrophilin Subfamily 3 Member A1 is produced by our Mammalian expression system and the target gene encoding Gln30-Gly254 is expressed with a Fc, Avi tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Comment

    58-62 kDa

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))

    Alternative Name

    BTN3A1

    Background

    Background: Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families. BTN3A1 acts as a critical protein for the activation of Vγ9Vδ2 T cells following detection of distressed cells. The anti-tumor responses of Vγ9Vδ2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.

    Synonym: Butyrophilin subfamily 3 member A1, CD277, BTN3A1, BTF5

    Molecular Weight

    52.6 kDa

    UniProt

    O00481

    Pathways

    Activated T Cell Proliferation
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