CEA Protein (Biotin,His-Avi Tag)
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- Target See all CEA Proteins
- CEA (Carcinoembryonic Antigen Gene Family (CEA))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This CEA protein is labelled with Biotin,His-Avi Tag.
- Purpose
- Recombinant Human CEACAM5/CD66e/CEA (C-6His-Avi) Biotinylated
- Sequence
- Lys35-Ala685
- Characteristics
- Biotinylated Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 is produced by our Mammalian expression system and the target gene encoding Lys35-Ala685 is expressed with a Avi, 6His tag at the C-terminus.
- Purity
- >95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CEA Protein
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- Comment
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110-150 kDa
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CEA (Carcinoembryonic Antigen Gene Family (CEA))
- Alternative Name
- CEA (CEA Products)
- Synonyms
- RGD1311281 Protein, carcinoembryonic antigen-related cell adhesion molecule 20 Protein, carcinoembryonic antigen gene family Protein, Ceacam20 Protein, Cea Protein
- Background
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Background: Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell-cell recognition. CEACAM5, also called CEA and CD66e, is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells, and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas, and its overexpression can protect tumor cells from apoptosis. It is commonly used as a cancer marker.
Synonym: Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen, CEA, Meconium antigen 100, CD66e, CEACAM5
- Molecular Weight
- 74.2 kDa
- UniProt
- P06731
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