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SARS-CoV Spike Protein (R667A, Trimer) (His tag)

Recombinant SARS-CoV Spike protein expressed in HEK-293 Cells.
Catalog No. ABIN7271647

Quick Overview for SARS-CoV Spike Protein (R667A, Trimer) (His tag) (ABIN7271647)

Target

See all SARS-CoV Spike (SARS-CoV S) Proteins
SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))

Protein Type

Recombinant

Origin

  • 18
  • 1
SARS Coronavirus GD01

Source

  • 10
  • 8
  • 1
HEK-293 Cells

Purity

>90 % as determined by SDS-PAGE.

Grade

MALS verified
  • Protein Characteristics

    R667A, Trimer

    Purification tag / Conjugate

    This SARS-CoV Spike protein is labelled with His tag.

    Purpose

    SARS-CoV GD01 Spike Trimer (R667A, KV968-969PP), His Tag (MALS verified)

    Sequence

    Ser 14 - Pro 1195

    Characteristics

    SARS-CoV GD01 Spike Trimer, His Tag (SPN-S52Ht) is expressed from human 293 cells (HEK293). It contains AA Ser 14 - Pro 1195 (Accession # AAP51227.1 (R667A, KV968-969PP).

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Application Notes

    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 136.5 kDa. The protein migrates as kDa under reducing (R) condition due to glycosylation.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS

    Storage

    -20 °C

    Storage Comment

    -20°C
  • Target

    SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))

    Alternative Name

    SARS-CoV Spike

    Background

    Synonyms:Spike,S protein,Spike glycoprotein,S glycoprotein,Description:It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

    Molecular Weight

    136.5 kDa
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