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Aspartate beta Hydroxylase Protein (AA 324-741) (His tag)

ASPH Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7273879
  • Target See all Aspartate beta Hydroxylase (ASPH) Proteins
    Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 324-741
    Origin
    • 14
    • 2
    Mouse
    Source
    • 5
    • 5
    • 2
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Aspartate beta Hydroxylase protein is labelled with His tag.
    Purpose
    Mouse ASPH Protein
    Sequence
    Ile324-Ile741
    Characteristics
    Recombinant Mouse ASPH Protein is expressed from E.coli with His tag at the N-Terminus.It contains Ile324-Ile741.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))
    Alternative Name
    ASPH (ASPH Products)
    Synonyms
    AAH Protein, BAH Protein, CASQ2BP1 Protein, HAAH Protein, JCTN Protein, junctin Protein, 2310005F16Rik Protein, 3110001L23Rik Protein, AI848629 Protein, AW261690 Protein, AW561901 Protein, C79816 Protein, cI-37 Protein, aah Protein, bah Protein, jctn Protein, MGC107896 Protein, cb971 Protein, fb69e10 Protein, fc06d04 Protein, fc95a08 Protein, wu:fb69e10 Protein, wu:fc06d04 Protein, wu:fc95a08 Protein, aspartate beta-hydroxylase Protein, aspartate-beta-hydroxylase Protein, aspartate beta-hydroxylase L homeolog Protein, ASPH Protein, Asph Protein, asph Protein, asph.L Protein
    Background
    Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis.
    Molecular Weight
    49.4 kDa same as Tris-Bis PAGE result.
    Pathways
    Positive Regulation of Endopeptidase Activity
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