BACE1 Protein (AA 22-457) (His tag)
-
- Target See all BACE1 Proteins
- BACE1 (Beta-secretase 1 (BACE1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-457
-
Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BACE1 protein is labelled with His tag.
- Purpose
- Mouse BACE-1 Protein
- Sequence
- Thr22-Thr457
- Characteristics
- Recombinant Mouse BACE-1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr22-Thr457.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product BACE1 Protein
-
Beta-secretase 1 (BACE1) (AA 22-457) protein (Fc Tag)
BACE1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Beta-secretase 1 (BACE1) (AA 22-457) protein (His tag)BACE1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Beta-secretase 1 (BACE1) (AA 46-152) protein (His-IF2DI Tag)BACE1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Beta-secretase 1 (BACE1) (AA 22-501) protein (GST tag)BACE1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Beta-secretase 1 (BACE1) (Active) protein (His tag)BACE1 Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Beta-secretase 1 (BACE1) (AA 22-457) protein (His tag)Crystallography grade BACE1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Beta-secretase 1 (BACE1) (AA 22-457) protein (His tag)Crystallography grade BACE1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Beta-secretase 1 (BACE1) (AA 46-501) protein (rho-1D4 tag)Crystallography grade BACE1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Beta-secretase 1 (BACE1) (AA 46-501) protein (rho-1D4 tag)Crystallography grade BACE1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Beta-secretase 1 (BACE1) (AA 22-457) proteinBACE1 Origin: Human Host: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE.
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- BACE1 (Beta-secretase 1 (BACE1))
- Alternative Name
- BACE-1 (BACE1 Products)
- Synonyms
- ASP2 Protein, BACE Protein, HSPC104 Protein, C76936 Protein, Bace Protein, MGC145931 Protein, BACE1 Protein, zgc:77409 Protein, beta-secretase 1 Protein, beta-site APP cleaving enzyme 1 Protein, beta-site APP-cleaving enzyme 1 Protein, BACE1 Protein, Bace1 Protein, bace1 Protein
- Background
- The beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) initiates the generation of amyloid-β (Aβ), and the amyloid cascade leading to amyloid plaque deposition, neurodegeneration, and dementia in Alzheimer's disease (AD). Clinical failures of anti-Aβ therapies in dementia stages suggest that treatment has to start in the early, asymptomatic disease states.
- Molecular Weight
- 49.49 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- UniProt
- P56818
-
