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CCL24 Protein (AA 27-119) (His tag)

CCL24 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274047
  • Target See all CCL24 Proteins
    CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 27-119
    Origin
    • 10
    • 7
    • 4
    • 2
    Human
    Source
    • 14
    • 5
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CCL24 protein is labelled with His tag.
    Purpose
    Human CCL24 Protein
    Sequence
    Val27-Cys119
    Characteristics
    Recombinant Human CCL24 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Val27-Cys119.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human CCL24, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Anti-CCL24 Antibody, hFc Tag with the EC50 of 26.9ng/ml determined by ELISA. See testing image for detail.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl, 100 mM L-arginine ( pH 7.5). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))
    Alternative Name
    CCL24 (CCL24 Products)
    Synonyms
    Ckb-6 Protein, MPIF-2 Protein, MPIF2 Protein, SCYA24 Protein, CKb-6 Protein, Scya24 Protein, C-C motif chemokine ligand 24 Protein, chemokine (C-C motif) ligand 24 Protein, CCL24 Protein, Ccl24 Protein
    Background
    C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fibrosis. It was found to be significantly expressed in patients with non-alcoholic steatohepatitis, in whom it regulates profibrotic processes in the liver.
    Molecular Weight
    11.9 kDa. Due to glycosylation, the protein migrates to 20-25 kDa based on Tris-Bis PAGE result.
    UniProt
    O00175
    Pathways
    Regulation of Actin Filament Polymerization
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