CD93 Protein (CD93) (AA 22-580) (Fc Tag)
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- Target See all CD93 Proteins
- CD93
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-580
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD93 protein is labelled with Fc Tag.
- Purpose
- Human CD93/C1q R1 Protein
- Sequence
- Thr22-Lys580
- Characteristics
- Recombinant Human CD93/C1q R1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Thr22-Lys580.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IGFBP-7, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human CD93, hFc Tag with the EC50 of 2.6μg/ml determined by ELISA. See testing image for detail.
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CD93 (CD93) (AA 22-580) protein (His-Avi Tag,Biotin)
CD93 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD93 (CD93) (AA 33-140) protein (GST tag)CD93 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
CD93 (CD93) (AA 24-580) protein (GST tag)CD93 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CD93
- Alternative Name
- CD93 (CD93 Products)
- Synonyms
- 6030404G09Rik Protein, AA145088 Protein, AA4.1 Protein, AW555904 Protein, C1qr1 Protein, C1qrp Protein, Ly68 Protein, C1QR1 Protein, C1qR(P) Protein, C1qRP Protein, CDw93 Protein, ECSM3 Protein, MXRA4 Protein, dJ737E23.1 Protein, C1qRp Protein, CD93 antigen Protein, CD93 molecule Protein, Cd93 Protein, CD93 Protein
- Background
- CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperresponsiveness and inflammation with Th2 cytokine activation, along with decreased CD93 expression in bronchial epithelial cells and lung homogenates but increased serum CD93 levels.
- Molecular Weight
- 85 kDa. Due to glycosylation, the protein migrates to 115-120 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9NPY3
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