CX3CL1 Protein (AA 25-341) (His tag)

Catalog No. ABIN7274439

Product Details

Target: CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

Protein Type: Recombinant

Protein Characteristics: AA 25-341

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CX3CL1 protein is labelled with His tag.

Purpose: Human CX3CL1/Fractalkine Protein

Sequence: Gln25-Gln341

Characteristics: Recombinant Human CX3CL1/Fractalkine Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln25-Gln341.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

Alternative Name: CX3CL1 (CX3CL1 Products)

Synonyms: ABCD3 Protein, CX3CL1 Protein, DKFZp459K117 Protein, Cx3c Protein, Scyd1 Protein, ABCD-3 Protein, C3Xkine Protein, CXC3 Protein, CXC3C Protein, NTN Protein, NTT Protein, SCYD1 Protein, fractalkine Protein, neurotactin Protein, AB030188 Protein, AI848747 Protein, CX3C Protein, Cxc3 Protein, D8Bwg0439e Protein, ATP binding cassette subfamily D member 3 Protein, C-X3-C motif chemokine ligand 1 Protein, chemokine (C-X3-C motif) ligand 1 Protein, ABCD3 Protein, CX3CL1 Protein, Cx3cl1 Protein, Abcd3 Protein

Background: Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer patients, although it is also associated with a poorer prognosis in some types of cancers, such as pancreatic ductal adenocarcinoma.

Molecular Weight: 34.7 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.

Pathways: Synaptic Membrane