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DR3/LARD Protein (AA 31-196) (His tag)

TNFRSF25 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274495
  • Target See all DR3/LARD (TNFRSF25) Proteins
    DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 31-196
    Origin
    • 12
    • 2
    • 1
    • 1
    Mouse
    Source
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This DR3/LARD protein is labelled with His tag.
    Purpose
    Mouse DR3/TNFRSF25 Protein
    Sequence
    Gln31-Met196
    Characteristics
    Recombinant Mouse DR3/TNFRSF25 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln31-Met196.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
    Alternative Name
    DR3 (TNFRSF25 Products)
    Synonyms
    APO-3 Protein, DDR3 Protein, DR3 Protein, LARD Protein, TNFRSF12 Protein, TR3 Protein, TRAMP Protein, WSL-1 Protein, WSL-LR Protein, Tnfrsf12 Protein, Wsl Protein, TNFRSF25 Protein, TNF receptor superfamily member 25 Protein, tumor necrosis factor receptor superfamily, member 25 Protein, TNFRSF25 Protein, Tnfrsf25 Protein
    Background
    TNF-like ligand 1 A (TL1A) and death receptor 3 (DR3) are a ligand-receptor pair involved in the pathogenesis of inflammatory bowel disease. Group 3 innate lymphoid cells (ILC3s) regulate intestinal immunity and highly express DR3.
    Molecular Weight
    18.79 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result.
    UniProt
    B1AWN9
    Pathways
    Apoptosis
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