Folate Receptor 4 Protein (AA 20-222) (His tag)
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- Target See all Folate Receptor 4 (FOLR4) products
- Folate Receptor 4 (FOLR4) (Folate Receptor 4 (Delta) (FOLR4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-222
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Folate Receptor 4 protein is labelled with His tag.
- Purpose
- Mouse FOLR4/Juno Protein
- Sequence
- Gly20-Gly222
- Characteristics
- Recombinant Mouse FOLR4/Juno Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly20-Gly222.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Folate Receptor 4 (Delta) (FOLR4) (AA 20-228) protein (His tag)
FOLR4 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 4 (Delta) (FOLR4) protein (His tag)FOLR4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Folate Receptor 4 (Delta) (FOLR4) proteinFOLR4 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Folate Receptor 4 (FOLR4) (Folate Receptor 4 (Delta) (FOLR4))
- Alternative Name
- FOLR4 (FOLR4 Products)
- Synonyms
- 0910001L11Rik Protein, C86255 Protein, Folbp3 Protein, IZUMO1 receptor, JUNO Protein, Izumo1r Protein, IZUMO1R Protein
- Background
- Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno, formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Juno are both healthy but sterile. Here, both sperm-egg binding proteins are shown to be evolving under positive selection. Juno's presence in mammals alone, suggesting a recent mammalian-specific duplication and neofunctionalization of the ancestral folate receptor.
- Molecular Weight
- 24.7 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result.
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