GGT1 Protein (AA 27-569) (His tag)

Catalog No. ABIN7274744

Product Details

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Protein Type: Recombinant

Protein Characteristics: AA 27-569

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This GGT1 protein is labelled with His tag.

Purpose: Human GGT1 Protein

Sequence: Pro27-Tyr569

Characteristics: Recombinant Human GGT1 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Pro27-Tyr569.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Alternative Name: GGT1 (GGT1 Products)

Synonyms: ggt1 Protein, zgc:64172 Protein, CD224 Protein, D22S672 Protein, D22S732 Protein, GGT Protein, GGT 1 Protein, GTG Protein, GGT-1 Protein, Ggtp Protein, dwg Protein, GGLUT Protein, Ggt Protein, GGT2 Protein, cd224 Protein, ggt Protein, gtg Protein, GGT1 Protein, ggt1-a Protein, gamma-glutamyltransferase 1a Protein, gamma-glutamyltransferase 1 Protein, gamma-glutamyltranspeptidase 1 Protein, gamma-glutamyltransferase 1 L homeolog Protein, gamma-glutamyltransferase Protein, gamma-glutamyltranspeptidase Ggt1 Protein, ggt1a Protein, GGT1 Protein, Ggt1 Protein, ggt1 Protein, LOC470168 Protein, ggt1.L Protein, ggt Protein, Bcep18194_A6223 Protein, h16_A1098 Protein, Shewana3_2487 Protein, Bcep1808_2978 Protein

Background: Gamma-glutamyl transferase (GGT, EC 2.3.2.2) is the only enzyme capable of degrading glutathione (GSH) in extra-cytosolic spaces. Overexpression of γ-glutamyl transpeptidase (GGT1) has been implicated in an array of human diseases including asthma, reperfusion injury, and cancer.

Molecular Weight: 59.69 kDa. Due to enzyme lysis and glycosylation, the protein migrates to 55-65 kDa (heavy chain) and 25-30 kDa (light chain) based on Tris-Bis PAGE result.