CD235a/GYPA Protein (AA 20-91) (Fc Tag)
-
- Target See all CD235a/GYPA (GYPA) Proteins
- CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-91
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD235a/GYPA protein is labelled with Fc Tag.
- Purpose
- Human GPA Protein
- Sequence
- Ser20-Glu91
- Characteristics
- Recombinant Human GPA Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser20-Glu91.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 1.16 μM as determined in SPR assay (Biacore T200). See testing image for detail.
-
Glycophorin A (GYPA) (AA 1-108) protein (Fc Tag)
GYPA Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glycophorin A (GYPA) (AA 20-91) protein (His tag)GYPA Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glycophorin A (GYPA) (AA 1-150) protein (GST tag)GYPA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Glycophorin A (GYPA) (AA 20-91) protein (His-DYKDDDDK-Strep II Tag)GYPA Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Glycophorin A (GYPA) (AA 1-108) protein (His tag)GYPA Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Glycophorin A (GYPA) (AA 20-150) protein (His-IF2DI Tag)GYPA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Glycophorin A (GYPA) (AA 1-108) protein (His tag)Crystallography grade GYPA Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glycophorin A (GYPA) (AA 1-168) protein (Strep Tag)Crystallography grade GYPA Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Glycophorin A (GYPA) (AA 20-150) protein (rho-1D4 tag)Crystallography grade GYPA Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
- Alternative Name
- GPA (GYPA Products)
- Synonyms
- GYPA Protein, gpa Protein, AI853584 Protein, CD235a Protein, GPA Protein, GPErik Protein, GPSAT Protein, HGpMiV Protein, HGpMiXI Protein, HGpSta(C) Protein, MN Protein, MNS Protein, PAS-2 Protein, glycophorin A (MNS blood group) Protein, glycophorin A Protein, GYPA Protein, Gypa Protein
- Background
- Granulomatosis with polyangiitis (GPA) presents a wide spectrum of manifestations from the common respiratory symptoms to infrequent neurological and cardiac complications. The challenge in diagnosis and management makes the rapidly progressive disorder one of the most challenging dilemmas in clinical medicine.The ultimate goal is an improved prognosis through outcome measures which assesses the disease control with minimal adverse effects of intensive immunosuppressive regimens, an integral part of the clinical approach to improve the quality of life of GPA patients.
- Molecular Weight
- 34.7 kDa. Due to glycosylation, the protein migrates to 45-70 kDa based on Tris-Bis PAGE result.
- Pathways
- Maintenance of Protein Location
-
