HLAG Protein (Tetramer) (PE,HLA-G)
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- Target See all HLAG Proteins
- HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
- Protein Type
- Recombinant
- Protein Characteristics
- Tetramer
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HLAG protein is labelled with PE,HLA-G.
- Purpose
- PE-Labeled Human HLA-G & B2M & Peptide (RIIPRHLQL) Tetramer Protein
- Sequence
- Gly25-Thr305 (HLA-G), Ile21-Met119 (B2M) and RIIPRHLQL peptide
- Specificity
- Uni-Prot: P17693-1 (HLA-G), P61769 (B2M), RIIPRHLQL
- Characteristics
- Recombinant PE-Labeled Human HLA-G & B2M & Peptide (RIIPRHLQL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Human HLA-G & B2M & Peptide (RIIPRHLQL) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305 (HLA-G), Ile21-Met119 (B2M) and RIIPRHLQL peptide.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product HLAG Protein
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HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (Tetramer) protein (HLA-G)
HLAG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (Tetramer) protein (HLA-G)HLAG Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (Tetramer) protein (Biotin,HLA-G)HLAG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (Monomer) protein (Biotin,HLA-G)HLAG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (Tetramer) protein (HLA-G)HLAG Origin: Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (Monomer) protein (HLA-G)HLAG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (Monomer) protein (HLA-G)HLAG Origin: Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (Monomer) protein (HLA-G)HLAG Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (AA 1-338) protein (GST tag)HLAG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (AA 25-308) protein (His tag)Crystallography grade HLAG Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS, 0.2 % BSA ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 6 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
- Alternative Name
- HLA-G (HLAG Products)
- Synonyms
- MHC-G Protein, B-F Protein, B-F-S04 Protein, B-F-S05 Protein, B-F-S06 Protein, B-F-S07 Protein, B-FI Protein, B-FIV Protein, BF2 Protein, BFa2 Protein, BFw-03 Protein, BFw-05 Protein, BFz-01 Protein, major histocompatibility complex, class I, G Protein, MHC BF1 class I Protein, HLA-G Protein, BF1 Protein
- Background
- HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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