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IL-20 Protein (AA 25-176) (His tag)

IL20 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274930
  • Target See all IL-20 (IL20) Proteins
    IL-20 (IL20) (Interleukin 20 (IL20))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 25-176
    Origin
    • 12
    • 5
    • 3
    • 1
    Mouse
    Source
    • 12
    • 4
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This IL-20 protein is labelled with His tag.
    Purpose
    Mouse IL-20 Protein
    Sequence
    Leu25-Leu176
    Characteristics
    Recombinant Mouse IL-20 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Leu25- Leu176.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 14.26 μM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in 20 mM PB, 500 mM NaCl ( pH 8.0).
    Storage
    -80 °C
    Storage Comment
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IL-20 (IL20) (Interleukin 20 (IL20))
    Alternative Name
    IL-20 (IL20 Products)
    Synonyms
    IL-20 Protein, IL10D Protein, ZCYTO10 Protein, Zcyto10 Protein, IL20 Protein, interleukin 20 Protein, IL20 Protein, Il20 Protein
    Background
    Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC.
    Molecular Weight
    19.5 kDa. Due to glycosylation, the protein migrates to 20-22 kDa based on Tris-Bis PAGE result.
    UniProt
    Q9JKV9
    Pathways
    Protein targeting to Nucleus
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