IL15RA Protein (AA 31-205) (Fc Tag)
Quick Overview for IL15RA Protein (AA 31-205) (Fc Tag) (ABIN7275020)
Target
See all IL15RA ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 31-205
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Purification tag / Conjugate
- This IL15RA protein is labelled with Fc Tag.
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Purpose
- Human IL-15RA/IL-15 R alpha/CD215 Protein
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Sequence
- Ile31-Thr205
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Characteristics
- Recombinant Human IL-15RA/IL-15 R alpha/CD215 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile31-Thr205.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human IL-15, No Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-15RA, hFc Tag with the EC50 of 61.2ng/ml determined by ELISA. See testing image for detail.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
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Alternative Name
- IL-15RA
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Background
- Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development.
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Molecular Weight
- 45.1 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
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UniProt
- Q13261-1
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Pathways
- JAK-STAT Signaling
Target
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