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IL15RA Protein (AA 31-205) (Fc Tag)

Recombinant IL15RA protein expressed in HEK-293 Cells.
Catalog No. ABIN7275020

Quick Overview for IL15RA Protein (AA 31-205) (Fc Tag) (ABIN7275020)

Target

See all IL15RA Proteins
IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Protein Type

Recombinant

Origin

  • 13
  • 5
  • 1
Human

Source

  • 9
  • 3
  • 3
  • 2
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Protein Characteristics

    AA 31-205

    Purification tag / Conjugate

    This IL15RA protein is labelled with Fc Tag.

    Purpose

    Human IL-15RA/IL-15 R alpha/CD215 Protein

    Sequence

    Ile31-Thr205

    Characteristics

    Recombinant Human IL-15RA/IL-15 R alpha/CD215 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile31-Thr205.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human IL-15, No Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-15RA, hFc Tag with the EC50 of 61.2ng/ml determined by ELISA. See testing image for detail.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

    Alternative Name

    IL-15RA

    Background

    Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development.

    Molecular Weight

    45.1 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.

    UniProt

    Q13261-1

    Pathways

    JAK-STAT Signaling
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